Week 7: Nucleophilic Substitution Part 2

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Overview:

This week we will continue with our nucleophilic substitution project by using recrystalllization to purify our product.
We will analyze our product using melting range, TLC, and ¹H NMR spectroscopy.

Reminders:

Come to lab dressed appropriately, with your PPE, and with your pre-lab work done. If not, you will not be able to participate in your lab section.
You MUST complete the following to before your lab section to participate in lab. You don't need to turn anything in before lab, but your TA will check a the beginning of class.
- Prepare your LabArchives (ELN) page for the experiment, including the following sections:
  - Objective - Includes structures for compounds used in lab.
  - How will you know if you have met the objective
  - Safety table (GHS)
  - Equipment table
  - Waste table
  - Procedure
We are back to regular in-person lab sections for all remaining weeks of the quarter.
- If you cannot attend your lab section, use the token form (link on Canvas Home page) to request a make-up lab for 3 tokens or you may choose to skip the lab period (you will not be able to complete the post-lab assignment if you skip).
- If you test positive for COVID, have any symptoms and have not been able to test, or have been instructed to isolate/sequester, please do not attend your lab section. Use the token form to request a make-up.
- Don't hoard tokens. They are intended to be used. You will have opportunities to earn more soon.


Lab Lectures
Week 7 Lab Lecture Preparation Week 7 Lab Lecture Slides Google Slides Version PDF version -> Open Google Slides -> File -> Download -> PDF Post-lab advice from LAs Week 7 Lab Lecture Video & Make-Up Assignment


Pre-Lab & In-Lab Materials
Pre-Lab Materials & Assignments Videos & Quizzes [Due: One hour before the start of your lab section ] Recrystallization Videos Recrystallization Pre-Lab Video Quiz Safety Reading Laboratory Safety for Chemistry Students (you already have this but it's linked again here just in case) 7.3.1 - Just the sections listed below Heating Recrystallization Vacuum Pumps, House Vacuum, and Water Aspirators (We use vacuum pumps in our class.) Experiment Handout & Other Tools Experiment Handout Vacuum Pump Instructions DigiMelt Instructions Keeping Our Labs Clean! Chem 51L Massive Safety Violation Policy Achieve Assignment: [Due: One hour before the start of your lab section ] Achieve Prelab Assignment Pre-Lab Notebook Assignment Complete pre-lab work in your notebook BEFORE your lab section meets. You do not need to submit this work yet, but your TA will check your notebook at the beginning of your lab section to make sure you completed the work. Need a reminder on what to do? Check out the Chem 51L ELN guidelines.	In-Lab Materials & Assignments In-Lab Experiment Activity At the beginning of your lab period, work with your partner(s) to complete the Jamboard Activity assignment linked in your LabArchives page. Insert screenshots of your team's answers where indicated. Complete the experimental procedures and collect any necessary data during your lab period. Keep track of experimental work as you go. In your notebook you should include answers to all of the questions in red font from the Experiment Handout. In your notebook you should include Observations made during the experimental procedures Any modifications made to the experimental procedures (running account column) Any data collected during your experiment Record Your Lab Technique As part of your final grade for the class, you will need to submit and earn credit for an annotated short video recording of yourself performing technique(s) in lab. Check the class grade tracker to determine how many technique videos you need to submit and pass for your target grade. This week you can choose to record one of the following techniques. Melting range (aka melting point) TLC Recrystallization See the general technique video assessment instructions and the individual assignments for information on what needs to be included with your video. We do not need to see every single moment. Instead, we want to see key pieces. Work with your partner(s) to help each other record. Each of you will need to submit your own video of yourself. It's loud in the lab rooms. Don't try to record your voice during lab. You can audio or text later. Aim to collect all video that you need during lab. You will have time outside of lab to edit your video. In-Lab Notebook Assignment In-Lab 5 [ Due: Day after your lab, 11:59 pm PST ]

Additional Resources

Technique Resources

TLC Videos (if you need to review)
Melting Range Videos (if you need to review)
Spectroscopy Videos (if you need to review)
NMR Solvent Impurities Table

Proficiency Exam Practice

Proficiency Exam Practice Question 2
- Proficiency Exam Practice Question 2 Solution

Post-Lab Assignment

Post-Lab Instructions

Project 2 Nucleophilic Substitution Post-Lab Instructions

Post-Lab Assignment & Rubric: [ Due: On your lab day, Week 8, 11:59 pm PST ]

Project 2 Nucleophilic Substitution Post-Lab Assignment (with rubric)

Click the Next button below or the above links to participate in weekly assignments!